IUPAC name: Eburnamenine-14-carboxylic acid ethylester

Assay: (perch. acid titr.) Not less than 99%

Product Origins: Vinpocetine is a derivative of the alkaloid Vincamine. Vincamine is found in the aerial part of Vinca minor plant and can also be derived from other plant sources such as the Voaconga and the crioceras longiflorus. The Vinca minor plant is a creeping root plant which has a long history of use as a traditional tonic to refresh weariness, especially the type associated with advanced age, and also as an astringent, for excessive menses, bleeding gums and mouth sores. Linnea's Vincamine is derived from Tabersonine, which is in turn the alkaloid extract of Voacanga seeds found primarily in the West Africa.

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Pharmacological Activities: Vinpocetine is held to exhibit an activity on neuronal metabolism by favouring the aerobic glycolysis and promoting the redistribution of the blood flow towards ischemic areas. Vinpocetine is also reported to act to increase cerebral circulation and the utilisation of oxygen.

Therapeutic Applications: Vinpocetine is commonly used as a "smart drug", as an aid to improving memory, as an aid in activities requiring highly focused attention and concentration such as technical writing or computer operation and to combat the symptoms of senile dementia. Vinpocetine has also been reported as showing promising results in the treatment of tinnitus or ringing in the ears as well as other causes of impaired hearing. Vinpocetine is also indicated in the treatment of strokes, menopausal symptoms and macular degeneration. Literature suggests Vinpocetine may also act to improve conditions related to insufficient blood flow to the brain including vertigo and MeniereÕs syndrome, difficulty in sleeping, mood changes and depression.

Therapeutical Categories: Vasodilator, Anti-ischemic

Synonyms: Ethyl-apovincaminate; 3 *, 16 * -apovincaminic acid-ethyl-ester