IUPAC name: (3a, 14a, 16a)- 14, 15-Dihhydro-14-hydroxyeburnamenine 14-carboxylic acid methylester

Assay: (perch. acid titr.) Between 98,5% and 101,5% or (DAC) between 99,0% and 101,0%

Product Origins: Vincamine is found in the aerial part of Vinca minor plant and can also be derived from other plant sources such as the Voaconga and the crioceras longiflorus. The Vinca minor plant is a creeping root plant which has a long history of use as a traditional tonic to refresh weariness, especially the type associated with advanced age, and also as an astringent, for excessive menses, bleeding gums and mouth sores. Linnea's Vincamine is derived from Tabersonine, which is in turn the alkaloid extract of Voacanga seeds found primarily in the West Africa.

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Pharmacological Activities: Vincamine is held to exhibit an activity on neuronal metabolism by favouring the aerobic glycolysis and may act to promote the redistribution of the blood flow towards ischemic areas. Vincamine also acts to increase cerebral circulation and the utilisation of oxygen.

Therapeutic Applications: Vincamine is known primarily as a vasodilator and is in general use as an aid in activities requiring highly focused attention and concentration such as technical writing or computer operation. Vincamine has also been indicated in the treatment of tinnitus or ringing in the ears and for the treatment of poor memory.

Therapeutical Categories: Vasodilator and anti-ischemic