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• Bilberry extract 25

• Centella asiatica purified triterpenes

• Ginkgo biloba extract EPG 246

• Ginkgo biloba extract G 328

• Ginkgo biloba extract G 320

• HMRlignan (TM)

• Hyoscine-N-butylbromide
(BP 2004 - EP V)

• L-5-Hydroxytryptophan
(Griffonia seed extract)

• Pilocarpine hydrochloride
(USP 28 - BP 2004 - EP V)

• Red Clover extract IFL 40

• Silymarin 80

• Troxerutin

• Vincamine (Fr. Xe - DAC 86)

• Vinpocetine (JPC 1993)

• Zea Mays insaponifiable fraction

 
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Ginkgo biloba extracts EPG 246, G328 and G320

Chemical definition: Mixture of Ginkgo flavonol glycosides, Ginkgo terpene lactones and Proanthocyanidins.

Assay:

  • Linnea EPG 246: 24% Ginkgo flavonglycosides, 6% Terpene lactones (Ginkolides and bilobalides balanced as per German monograph)
  • Linnea G 328: 32% Ginkgo flavonglycosides, 8% Terpene lactones
  • Linnea G 320: 32% Ginkgo flavonglycosides, without Terpene lactones (mainly used in cosmetic applications)

Product Origins: Linnea Ginkgo Biloba Extracts EPG 246, G 328 and G 320 are extracted from the leaves of the Ginkgo Biloba tree dating from the Palaeozoic era (350 million years ago). The Ginkgo Biloba tree, which is notable for high resistance to both pollutants and pests, has a long tradition of use in Oriental medicine; in particular for the treatment and control of respiratory and circulatory ailments and for brain function.

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Adobe PDF                   Click here to view the Linnea Botanical BriefTM

The name Ginkgo is derived from a wrong transcription of the Japanese name Yin-Kwo that means silver fruit, while the name biloba derives from the bilobed shape of its leaf.

Among the pharmacological active constituents those compounds with great importance are the flavonoids (ginkgo flavonol glycosides) and the terpene trilactones (ginkgolides and bilobalide). Different kind of flavonoids has been isolated from the ginkgo extracts. Those of therapeutic interest are glycosyl derivitives of quercitin and kaempferol respectively. Kaempferol is considered particularly relevant for the therapeutic efficacy.

Therapeutic Applications: Ginkgo biloba extract is believed to have a regulating effect on the entire vascular system of veins, arteries and capillaries. The most common usage of Gingko biloba extract is for its widely accepted effects in the regulation of blood flow to the brain, legs and other extremities. Also commonly cited for the control of the level of various neurotransmitters in the brain thus helping to counteract memory loss, depression and lack of alertness which may occur in old age.

A reported "smart drug" Ginkgo biloba extract may also promote the metabolism of cerebral and neurosensorial cells. Gingko biloba is also used to counteract a number of conditions such as vascular insufficiency and tinnitus and has also been indicated in the treatment of intermittent claudication (pain while walking). Recent studies have also indicated the potential use of Ginkgo biloba in the treatment of AlzheimerÕs disease. Ginkgo biloba extract is also a free radical scavenger and powerful antioxidant.

Cosmetic Applications: Include anti ageing, elimination of toxins, free radical scavenger, powerful antioxidant, strengthening of the skins defenses, improvement of dermal micro-circulation and stimulation of lymph drainage.

Therapeutical Categories: Vasodilator, Anti-ischemic, Free radical scavenger & Antioxidant

Synonyms: Maidenhair Tree